From its beginnings in 1984, ENDL focused on facilitating advances in storage technology with special emphasis on augmenting communications between the people responsible for storage technology standards, and the engineers who had to implement them. Some of those standards are still in daily use, such as ATA, SCSI and Fibre Channel.

As the decades passed, evolutionary changes in computing technologies affected the optimum means by which ENDL could fulfill its founder's goals. Before the internet became a favorite learning tool, ENDL Publications called upon expert authors to distill standards into easy-to-read descriptions best suited for product development engineers. The most successful of these books were the Bench References for SCSI and Fibre Channel.

In 1990, ENDL led the Small Form Factor Committee's effort to dimension 2.5" disk drives so they could be interchangeable in portable computers. When this effort expanded to all the form factors and definition of the ATAPI interface, it was re-titled as the SFF Committee. Today, the SFF Committee is best known for the variety of connectors and transceivers used by storage and Ethernet interfaces. In 2016, leadership of the SFF Committee transitioned to SNIA.

Through all the hurly-burly, the most famous (or infamous) of the ENDL communications projects was the ENDL Letter which occasionally was compared to a standards soap opera, The Days of Our Standards or at less flattering moments a grocery store tabloid. The ENDL Letter has been on ice since December 2012, waiting a respectful interval to ensure that what was once confidential is no longer very much of a secret.

Today, the ENDL principals are I. Dal Allan and Ralph O. Weber.